VISION: The vision of the Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M) is to bring together bioengineers, manufacturing engineers, and industrial engineers to work closely with cell biologists, clinicians, and industry partners to make cell therapy manufacturing a well-characterized, quality-controlled, efficient, and highly-reproducible process for broad clinical use.
MISSION: The Marcus Center will become one of the world’s premier authority for cell characterization, manufacturing, and scale-up process development. The Center will be recognized AND utilized as THE NATIONAL RESOURCE for standardization of cell-production, characterization, and potency determination.
The initial focus of the Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M) are in the areas of (a) mesenchymal stromal/stem cells (MSCs) from bone marrow and cord tissue for immune-modulation and tissue-biofabrication, (b) T and B cells for immunotherapies in cancer, infectious and autoimmune diseases; and (c) Cord blood and bone marrow hematopoietic stem cells for regenerative medicine. The Center will implement the National Roadmap for Cell Manufacturing, recently published by the National Cell Manufacturing Consortium and highlighted by the White House.
GOALS: The goals of the Marcus Center are to: