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VISION: The vision of the Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M) is to bring together bioengineers, manufacturing engineers, and industrial engineers to work closely with cell biologists, clinicians, and industry partners to make cell therapy manufacturing a well-characterized, quality-controlled, efficient, and highly-reproducible process for broad clinical use.

MISSION: The Marcus Center will become one of the world’s premier authority for cell characterization, manufacturing, and scale-up process development. The Center will be recognized AND utilized as THE NATIONAL RESOURCE for standardization of cell-production, characterization, and potency determination.

The initial focus of the Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M) are in the areas of (a) mesenchymal stromal/stem cells (MSCs) from bone marrow and cord tissue for immune-modulation and tissue-biofabrication, (b) T and B cells for immunotherapies in cancer, infectious and autoimmune diseases; and (c) Cord blood and bone marrow hematopoietic stem cells for regenerative medicine. The Center will implement the National Roadmap for Cell Manufacturing, recently published by the National Cell Manufacturing Consortium and highlighted by the White House.


GOALS: The goals of the Marcus Center are to:

  • Collaborate with clinical partners to identify the characteristics of cells that are associated with therapeutic potency in specific treatments;
  • Innovate and develop new methods for rapidly validating function, potency, and safety of manufactured cells;
  • Invent new tools and technologies for scale-up and scale-out of therapeutic cells (stem and progenitor cells, as well as immunotherapeutic cells);
  • Develop technologies for cell purification, separation, delivery, packaging, and storage while maintaining cell purity, numbers, and quality;
  • Enable low cost, reproducible, large-scale production of highly potent therapeutic cells by incorporating industrial design principles, automated robotics-based systems, supply-chain management, and manufacturing process-flow concepts;
  • Translate our engineering methodologies and new technologies to pre-clinical and clinical applications in collaboration with clinicians and industry partners; and
  • Help build a strong, well-trained workforce in cell manufacturing.

Uniqueness of the Marcus Center
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New Facilities and Interfacing with Existing Infrastructure
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Georgia Tech has already been chosen by the federal government to lead the nationwide consortium 
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© 2016 Cell Manufacturing and Petit Institute of Bioengineering and Bioscience


Parker H. Petit Institute for Bioengineering and Bioscience at Georgia Tech
315 Ferst Dr. NW, Atlanta, GA 30332-0363